Inter-observer Variation in Gross Tumor Delineation of Esophageal Cancer on MR, CT and PET CT

Institute of Oncology Ljubljana23 enrolled

Overview

The aim of the study is to investigate inter-observer variation in gross tumor volume (GTV) delineation of oesophageal cancer on different imaging modalities - CT, PET CT and MR.Twenty-three consecutive patients with esophageal cancer treated with preoperative or curative chemoradiotherapy were selected. All patients had CT, PET CT and MR imaging in treatment position prior to radiotherapy.Five experienced observers from our institution will independently delineate GTV on CT alone, MR alone, PET CT alone, on co-registered CT and MR and co-registered PET CT and MR. Inter-observer agreement, expressed in generalized conformity index (CIgen) and mean volumes of GTV will be calculated per patient and imaging modality.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Esophageal Cancer

Interventions

MR, PET CTOTHER

diagnostic method

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * locally advanced esophageal cancer eligible for treatment with preoperative or curative chemoradiotherapy Exclusion Criteria: * contraindications for MR

Locations (1)

Institute of Oncology

Ljubljana, Slovenia

Outcomes

Primary Outcomes

Change of interobserver variability in target volume delineation on CT, PET CT and MR.

To compare target volume delineation of esophageal cancer using CT, PET CT and MR with determining generalized conformity indexes and mean volumes of GTV.

Time frame: Through study completion, an average of 1 year.

Data from ClinicalTrials.gov

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