In this study, the microbiota sequencing was used to investigate the changes of microbiota in the terminal ileum and the middle part of ascending colon, the mesenteric adipose tissue of ileum and ascending mesocolon, and oral cavity of patients with Crohn's disease before and after ileocecal resection, so as to further explore the role of ileocecal region in inducing remission of disease.
Study Type
OBSERVATIONAL
Enrollment
60
Shanghai 10th People's Hospital
Shanghai, Shanghai Municipality, China
Microbial changes of intestinal mucosa
Explore the microbial changes in the mucosa of the terminal ileum and the middle segment of the ascending colon in patients with Crohn's disease before and after ileocecal resection through metagenomic analysis
Time frame: 6 month
Microbial changes of mesenteric adipose tissue
Explore the microbial changes in the mesenteric adipose tissue of the terminal ileum and the middle segment of the ascending colon in patients with Crohn's disease before and after ileocecal resection through metagenomic analysis
Time frame: 6 month
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