This study aims to investigate whether the use of nociception monitoring during general anesthesia with remimazolam-based total intravenous anesthesia has an effect on intraoperative opioid requirements and postoperative pain. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
58
Patients will receive remimazolam-based total intravenous general anesthesia with nociception monitoring with the ANI monitor
Patients will receive remimazolam-based total intravenous general anesthesia based on hemodynamic monitoring and without nociception monitoring
Yonsei University Health System, Severance Hospital
Seoul, South Korea
RECRUITINGIntraoperative remifentanil requirement
Intraoperative remifentanil requirements will be collected as primary outcome as µg/kg/min
Time frame: Within the intraoperative period
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