This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.
Purpose To evaluate whether the volume of wash out rinse after povidone iodine (PI) application for intravitreal injections (IVI) affects patients' ocular surface irritation. Methods This was a prospective, single-masked, randomized-controlled trial consisting of 142 subjects . A total of 51, 45, and 46 patients received 3-mL, 10-mL, and 15-mL of ocular rinse respectively. Reductions in the Ocular Surface Disease Index (OSDI) and the Standardized Patient Evaluation of Eye Dryness II (SPEED II) surveys, conducted before and at 24-72 hours post-injection, were analyzed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
142
Ocular Surface Disease Index
Standardized Patient Evaluation of Eye Dryness II questionnaire
Dean McGee Eye Institute
Oklahoma City, Oklahoma, United States
Ocular Surface Disease Index
Patient symptoms questionnaire, range 0-28, higher score is associated with worse outcome.
Time frame: 24-72 hours after injection
Standardized Patient Evaluation of Eye Dryness II
Patient symptoms questionnaire, range 0-48, higher score is associated with worse outcome.
Time frame: 24-72 hours after injection
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