Antibiotic Therapy in Infections of the Diabetic Foot Syndrome

University Hospital, Basel, Switzerland80 enrolled

Overview

This retrospective study examines the surgical and antibiotic treatment of diabetic foot syndrome infections treated at the University Hospital Basel since 2019. It analyses the implementation of the hospital in-house guidelines published in 2019 with regard to antibiotic therapy in diabetic foot infections, taking into account clinical, microbiological and histopathological criteria. The defined endpoints are (i) fully compliant with internal policies, (ii) partially compliant with internal policies, and (iii) not compliant with internal policies. The recording of these proportions is descriptive.

This retrospective study examines the surgical and antibiotic treatment of diabetic foot syndrome infections treated at the University Hospital Basel since 2019. (In 2019 the departments of infectiology and orthopedics at the University Hospital Basel published recommendations with regard to the duration of antibiotic therapy in infections of the diabetic foot syndrome. This depends on whether a surgical intervention was performed and takes into account both the microbiological and the histopathological samples). Data that are routinely collected in everyday clinical practice and stored in the hospitals' medical records will be evaluated. The aim of this research project is to check the implementation of these recommendations. Inadequate use of antibiotics should thus be recognized. The study has the aspect of quality control.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Diabetic Foot Infection

Interventions

Data collection in patients with diabetic foot syndrome and infections in the area of the footOTHER

Data collection: on (surgical and antibiotic) treatment and implementation of the recommendations published 2019 with regard to the duration of antibiotic therapy.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * soft tissue infection or bone infection (incl. osteomyelitis) in diabetic foot syndrome * inpatient stay at the University Hospital Basel between January 1st, 2019 and December 31st, 2021 * surgical intervention (amputation and/or debridement) * signed general consent Exclusion Criteria: * datasets without a diagnosis of the diabetic foot * no surgical intervention performed (amputation and/or debridement) * surgical interventions performed by disciplines other than orthopaedics/traumatology (e.g. vascular surgery) * infections in osteosynthesis material (implant or fracture-associated infections)

Locations (1)

University Hospital Basel, Orthopedics and Traumatology

Basel, Switzerland

Outcomes

Primary Outcomes

Compliance with the hospital in-house guidelines for diabetic foot infections with regard to antibiotic treatment

Implementation of the guidelines published in 2019 with regard to antibiotic therapy in diabetic foot infections, taking into account clinical, microbiological and histopathological criteria. The defined endpoints are (i) fully compliant with internal policies, (ii) partially compliant with internal policies, and (iii) not compliant with internal policies.

Time frame: one time assessment at baseline

Secondary Outcomes

Duration of antibiotic therapy (days)

Duration of antibiotic therapy

Time frame: one time assessment at baseline

Relapse of diabetic foot infections (number)

Time frame: one time assessment at baseline

Data from ClinicalTrials.gov

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