Effect of Paravertebral Muscle Fat Infiltration on Rocuronium Use in Lumbar Surgery

Early Phase 1CompletedNCT05619848

Zheng Guo87 enrolled

Overview

To investigate the effect of different degrees of fat infiltration on rocuronium use in lumbar surgery was monitored by trapezius muscle relaxation.

Select the patients who will receive posterior lumbar surgery in the Second Hospital of Shanxi Medical University. According to the classification criteria of fat infiltration, it will be divided into three groups: mild, moderate and severe. This study will pump and titrate rocuronium bromide under the monitoring of muscle relaxation during the operation, record the dosage of rocuronium bromide and the duration of pump injection, and evaluate its clinical effect. Postoperative results include the use and clinical effect of rocuronium, which will be counted after the trial.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Enrollment

Conditions

Spinal Stenosis Lumbar

Interventions

Rocuronium BromideDRUG

0.6 mg/kg rocuronium was injected intravenously, and rocuronium was pumped during operation to maintain deep muscle relaxation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: Age: 18-65; ASA grade I-II; no significant cardiopulmonary disease; no history of surgery in the corresponding surgical area; no coagulopathy. Exclusion Criteria: refusal to participate by the present experimenter; those with severe cardio-cerebrovascular disease, severe hepatic and renal dysfunction; taking medications affecting the neuromuscular junction; area of monitoring site for skin breakers; patients with intraoperative bleeding, anaphylactic shock, or other serious complications; patients requiring intraoperative neurophysiological monitoring (including sensory, motor evoked potentials).

Locations (1)

Second of Shanxi Medical University

Taiyuan, Shanxi, China

Outcomes

Primary Outcomes

use of rocuronium bromide

average dosage

Time frame: Perioperative period

Secondary Outcomes

The general condition of the paraspinal muscle

Fat infiltration rate

Time frame: Perioperative period

Data from ClinicalTrials.gov

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