Postprandial Lipemia and Glycemia Following a High-Fat Meal

N/ACompletedNCT05619952

State University of New York at Buffalo16 enrolled

Overview

The goal of this clinical trial is to determine the acute effects on postprandial lipemia and glycemia by supplementing a high-fat meal with either white button (WB) or shiitake (SH) mushroom powder in relatively healthy adults, aged 18 to 35.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Hypercholesterolemia Postprandial Hyperglycemia Lipid Disorder

Interventions

Mushroom PowderDIETARY_SUPPLEMENT

Ground shiitake mushrooms or ground white button mushrooms

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * generally healthy * non-diabetic * normal to mildly hypercholesterolemic (Total Cholesterol 200-239 mg/dL and LDL-C 130-159 mg/dL) * have BMI \<30 or BF% (men \<25%, women \<32%) * no known disease of the liver or gallbladder * no documented problems with fat metabolism * normal lipemic response to a lipid challenge * No known mushroom allergy Exclusion Criteria: * diabetic * pregnant * BMI \>30 * liver disease * gallbladder disease * mushroom allergy * lipid disorder

Outcomes

Primary Outcomes

Postprandial Lipemia

Total cholesterol, LDL, HDL, triglycerides

Time frame: Baseline, up to 6 hours postprandial

Postprandial Glycemia

blood glucose

Time frame: Baseline, up to 6 hours postprandial

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.