UNC Pleural Fluid Registry

N/ARecruitingNCT05620329

UNC Lineberger Comprehensive Cancer Center9,999 enrolled

Overview

Research with biospecimens such as blood, tissue, or body fluids can help researchers understand how the human body works. Researchers can make new tests to find diseases, understand how treatments work, or find new ways to treat a disease. The purpose of this study is to collect biospecimens for research from patients with known or suspected lung cancer. The information learned from the biospecimens may be used in future treatments. The purpose of this protocol is to create a pleural fluid registry for use in future studies.

Study Type

OBSERVATIONAL

Enrollment

9,999

Conditions

Lung Cancer Lung Infection Breast Cancer Malignant Pleural Effusion Empyema

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who are 18 years or older * Inpatients and outpatients * Diagnosed with pleural fluid, are referred for and undergo clinically indicated drainage who have clinical evidence of: * pulmonary infection (such as fever, leukocytosis, new or worsening infiltrate on chest x-ray, or clinical deterioration) with effusion * malignancy Exclusion Criteria: * A subject will not be eligible for inclusion in this registry if, in the investigator's (or treating clinician's) opinion, the patient has any concurrent medical condition that may preclude their ability to undergo pleural fluid drainage safely. * Incarcerated individuals

Outcomes

Primary Outcomes

Creation of a pleural fluid registry

Biological specimens and corresponding clinical data from subjects will be collected during standard of care procedures and medical record abstraction to support the creation of a pleural fluid registry.

Time frame: 32 years