Correlating the Measure of Retinal Vascular Density Through Angio-OCT with Calcium Score

Centre Hospitalier Universitaire de Besancon101 enrolled

Overview

Recent case-control studies have proven that the retinal vascularization mirrors the cardiac vascularization: more the coronary network is altered, more the density of retinal vessels is reduced. No studies have yet been realised in primary prevention. This study aims to demonstrate a link between the density of the retinal vascularization and the calcium score, which is currently the gold standard for the classification of cardiovascular risk in primary prevention. Thus, a simple image of the retinal vascularization could predict the cardiovascular risk of a patient. OCT angiography would become a major aid in the classification of cardiovascular risk in asymptomatic patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

101

Conditions

Cardiovascular Abnormalities Vascular Diseases Retinal Vascular

Interventions

Ophthalmologic consultationOTHER

Complete ophthalmologic examination including angio-OCT

Eligibility

Sex: ALLMin age: 40 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients eligible for a calcium score as part of their standard treatment and volunteers for an ophthalmologic consultation Exclusion Criteria: * Pregnant women

Locations (1)

CHU de Besançon

Besançon, France

Outcomes

Primary Outcomes

Correlation between retinal vascular density and calcium score

Comparison between values of calcium score and presence of vascular abnormalities in retina. Calcium is scored as follows: * Coronary Artery Calcium \[CAC\] = 0 : very low risk * CAC = \[1-100\[ : low risk * CAC = \[100-400\[ : moderate risque * CAC = \[400-1000\[ : high risk * CAC = \> 1000 : very high risk

Time frame: Day 1

Data from ClinicalTrials.gov

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