Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions

Lo.Li.Pharma s.r.l40 enrolled

Overview

To test the efficacy of a newly-commercialized formula, 40 HPV-positive women displaying chronic cervicitis, mild dysplasia or moderate dysplasia. Women in the study group took one tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid for twelve weeks. Women in the control group received no treatment.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Papilloma Cervix Lesion

Interventions

Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic AcidDIETARY_SUPPLEMENT

One tablet per day containing 200 mg of EGCG, 400 mcg of Folic Acid, 1 mg of Vitamin B12 and 50 mg of Hyaluronic Acid.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * HPV infections * Occurrence of low-grade cervical lesions Exclusion Criteria: * Diagnosis of malignancy or severe cervical lesions * Concurrent uterine pathologies * Pregnancy or intended to seek pregnancy in the next three months * Cancer

Locations (1)

Clinica Alma Res

Roma, Italy

Outcomes

Primary Outcomes

Regression of cervical lesions

The actual outcome was to measure the rate of regression of the lesions, from moderate to mild, from mild to none.

Time frame: 12 weeks

Data from ClinicalTrials.gov

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