Rationale: Combining statin treatment and physical activity is very effective for the prevention of cardiovascular diseases. Statins are well-tolerated by most patients, but may cause statin-associated muscle symptoms (SAMS). Objective: To identify predictors for SAMS in statin users and to objectively assess physical activity levels and sedentary time between symptomatic and asymptomatic statin users.
Combining statin treatment and physical activity is very effective for the prevention of cardiovascular diseases. Statins are well-tolerated by most patients, but may cause statin-associated muscle symptoms (SAMS). Physical activity may exacerbate SAMS, producing decreased physical activity levels or statin nonadherence. However, it is unknown if daily activity patterns differ between symptomatic and asymptomatic statin users. In this cross-sectional observational study the investigators will assess if physical activity levels and sedentary time differ between symptomatic and asymptomatic statins users. Secondly, questionnaires will be used to assess predictors of SAMS.
Study Type
OBSERVATIONAL
Enrollment
196
Physical activity patterns will be measured using the activPAL3 micro monitor
Department of Physiology
Nijmegen, Netherlands
Physical activity
Physical activity (min/day) will be assessed using the activPAL3 micro monitor
Time frame: during 1 week
Sedentary time
Sedentary time (min/day) will be assessed using the activPAL3 micro monitor
Time frame: during 1 week
Predictors of statin-associated muscle complaints (SAMS)
Using questionnaires predictors of SAMS will be explored
Time frame: 1 moment (cross-sectional)
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