Biomarker-s of Abusive Head Trauma by Proteomics

N/ANot Yet RecruitingNCT05626465

University Hospital, Geneva174 enrolled

Overview

The aim of our study is to highlight biomarker-s of Abusive Head Trauma by proteomics analyses on the serum of child victims of abuse.

Study Type

OBSERVATIONAL

Enrollment

174

Conditions

Abuse, Child Protein Disorder, Blood

Interventions

Blood testOTHER

Proteomic analyses on serum

Eligibility

Sex: ALLMax age: 2 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age : 0-2 y.o * Medical consultation for malaise, seizure (without fever), loss of consciousness, traumatic bain injury, or cranioplasty * Blood test during medical care * Accepted informed consent Exclusion Criteria: * Refused informed consent * For control groups : medical history of child abuse * For AHT group : rare metabolic disease (Menkes, etc..)

Locations (2)

Ginhoux Thiphanie

Lyon, Rhône, France

Wiskott Kim

Geneva, Switzerland

Outcomes

Primary Outcomes

Highlight novel biomarker-s of AHT

Proteomic analyses will be made on serum of infant victim of AHT. Results will be compare with control groups (traumatic brain injury, cranioplasty, malaise).

Time frame: Hospital admission to discharge (up to 3 days)

Central Contacts

Kim Wiskott, MD

CONTACT

0041797737424 kim.wiskott@hcuge.ch

Data from ClinicalTrials.gov

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