To date, the effects of pain on motor learning have not been thoroughly investigated. When examining potential effects on retention of motor learning, it is important to dissociate any effects of pain from effects of a context change. The purpose of this research is to determine whether any altered retention of motor learning associated with acute pain is a true affect of pain or an affect of context (or both).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
61
Experimental pain paradigm delivered (capsaicin cream combined with heat) that is short-term and painful but not harmful. Applied to skin just during the Day 1 learning period.
Experimental pain paradigm delivered (capsaicin cream combined with heat) that is short-term and painful but not harmful. Applied to skin during the Day 1 learning period and again during the Day 2 retention period.
University of Delaware
Newark, Delaware, United States
Motor Retention Magnitude
degree to which the learned locomotor pattern has been remembered (in step length percent change, normalized to the amount learned from day 1)
Time frame: 24 hours post learning (day 2)
Motor Learning Magnitude
degree to which the new locomotor pattern has been acquired (in step length percent change)
Time frame: immediately after learning (day 1)
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