Biomimetic Hydroxyapatite in Pediatric Patients With Asthma and/or Allergic Rhinitis

University of Pavia40 enrolled

Overview

The aim of the study is to compare the incidence of dental caries and the level of demineralization in pediatric patients with asthma and/or allergic rhinitis. Patients will conduct professional oral hygiene at the baseline. The following clinical indexes will be assessed: BEWE Index, Plaque Index, Bleeding Score, Schiff Air Index. Then, patients will be randomly divided into two groups: * Trial group: domiciliary use of Biorepair Total Protection Plus + desensitizing enamel-repair shock treatment twice a day * Control group: domiciliary use of Elmex Caries Protection twice a day The clinical indexes will be assessed again after 1 month (T1), after 3 (T2) and 6 months (T3).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Dental Caries Periodontal Diseases

Interventions

Eligibility

Sex: ALLMin age: 6 YearsMax age: 14 Years

Medical Language ↔ Plain English

Inclusion Criteria: * pediatric patients aged between 6-14 years * diagnosis of allergic rhinitis and asthma * therapy with salmeterol/fluticasone propionate * diffused enamel demineralizations of deciduous and permanent teeth Exclusion Criteria: * low cooperation according to grades 3 and 4 of Frankl behavioral scale * nonadherence to the study protocol checked by parents * other systemic diseases.

Outcomes

Primary Outcomes

Change of the BEWE Index - Basic Erosive Wear Examination (Barlet et al.2008)

Scoring criteria: 0 = no erosive tooth wear; 1. = initial loss of surface texture; 2. = distinct defect, hard tissue loss \< 50% of the surface area; 3. = hard tissue loss ≥ 50% of the surface area. The BEWE will be assessed with Intact Tooth application