The main objective is to assess the 6-month prognosis of patients who presented with extreme agitation in the emergency room. The primary endpoint is the 6-month mortality of agitated patients.
Emergency services are confronted with emergency situations characterized by patients who are victims of significant agitation, in particular states of extreme agitation "excited delirium syndrome", which is constantly increasing and which seems to be associated with morbidity and mortality not negligible. Patients meeting the inclusion and non-inclusion criteria are included on admission to the emergency room. An evaluation at H1 and at the end of hospitalization is carried out. The patient is contacted by telephone at M1, M3 and M6. The inclusion period is 24 months The duration of participation (treatment + follow-up) is 6 months The total duration is 30 months. The research is multicentric and national with the participation of 8 centres.
Study Type
OBSERVATIONAL
Enrollment
608
Avicenne Hospital - Aphp
Bobigny, Île-de-France Region, France
RECRUITINGNumber of deceased patients
The 6-month prognosis of patients who presented with extreme agitation in the emergency room.
Time frame: 6 months
Assess the characteristics of agitated patients regarding the age
Age
Time frame: 6 months
Assess the characteristics of agitated patients regarding the gender
Gender
Time frame: 6 months
Assess the characteristics of agitated patients regarding the mode of arrival in the emergency room
Mode of arrival in the emergency room
Time frame: 6 months
Assess the characteristics of agitated patients regarding medical history
Medical history
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (blood pressure)
Blood pressure
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (oxygen saturation)
Oxygen saturation
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (heart rate)
Heart rate
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (respiratory rate)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Respiratory rate
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (temperature)
Temperature
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (Glasgow coma scale)
Glasgow coma scale (The GCS is scored between 3 and 15, 3 being the worst and 15 the best).
Time frame: 6 months
Assess the characteristics of agitated patients regarding vital signs (Corrected QT interval on electrocardiogram)
Corrected QT interval (QTc)
Time frame: 6 months
Assess the characteristics of agitated patients regarding patient biology (blood ionogram)
Blood ionogram
Time frame: 6 months
Assess the characteristics of agitated patients regarding patient biology (urine and blood toxins)
Urine and blood toxins
Time frame: 6 months
Assess the characteristics of agitated patients regarding patient biology
Arterial blood gas
Time frame: 6 months
Assess the characteristics of agitated patients regarding patient biology (Complete blood count)
Complete blood count (CBC)
Time frame: 6 months
Assess the characteristics of agitated patients regarding agitation (RASS)
Agitation assessment scale (Richmond Agitation Sedation Scale, RASS) (-5 = worse outcome to +4 = worse outcome, 0 is the better outcome)
Time frame: 6 months
Assess the characteristics of agitated patients regarding agitation (BARS)
Agitation assessment scale (Behavioural Activity Rating Scale, BARS) (1 = worse outcome to 7 = worse outcome , 4 is the better outcome)
Time frame: 6 months
Assess the characteristics of agitated patients regarding agitation (CGI S)
Agitation assessment scale (Clinical Global Impression Severity or CGI S, 0 = Not evaluated to 7 = worse outcome)
Time frame: 6 months
Characterize the etiologies of this syndrome (organic, psychiatric or iatrogenic)
Organic * medical background, * somatic etiology research with intrinsic imputability criteria (chronological and semiological) and extrinsic (literature) * capillary blood glucose, temperature, Glasgow, electrocardiogram * blood ionogram, arterial blood gas, blood count Iatrogenic * analytical by means of a urinary and blood toxin screening for recent consumptions of psychoactive substances * search the treatment of the patient psychiatric * clinical observations obtained during consultation
Time frame: 6 months
Characterize the management of patients in extreme agitation according to initial pharmacological treatments administered
Initial pharmacological treatments administered
Time frame: 6 months
Characterize the management of patients in extreme agitation according to the need for physical restraints
Need for physical restraints
Time frame: 6 months
Characterize the management of patients in extreme agitation according to the eed for upper airway protection with intubation
Need for upper airway protection with intubation
Time frame: 6 months
Assess the efficacy of the pharmacological treatments administered (GCI S)
According to agitation scale at H1, H2 (Clinical Global Impression Severity or CGI S, 0 = Not evaluated to 7 = worse outcome) and need for other pharmacological treatments
Time frame: 6 months
Assess the efficacy of the non-pharmacological treatments administered (RASS)
According to agitation scale at H1, H2 (Richmond Agitation Sedation Scale, RASS) (-5 = worse outcome to +4 = worse outcome, 0 is the better outcome) and need for other non-pharmacological treatments
Time frame: 6 months
Assess the efficacy of the non-pharmacological treatments administered (BARS)
According to agitation scale at H1, H2 (Behavioural Activity Rating Scale, BARS) (1 = worse outcome to 7 = worse outcome , 4 is the better outcome) and need for other non-pharmacological treatments
Time frame: 6 months