Lung Ventilation and Perfusion in Different Phenotypes of Chronic Critical Illness With Prolonged Mechanical Ventilation

National Taiwan University Hospital103 enrolled

Overview

This project will conduct a series of analysis of physiological and clinical data on tracheostomy patients who receive prolonged mechanical ventilation, hoping to find out the different manifestations of patients through the investigation by a variety of physiologic measurements, so as to understand whether different types of patients phenotype to derive different clinical strategies for liberation of the mechanical ventilator.

Study Type

OBSERVATIONAL

Enrollment

103

Conditions

Prolonged Mechanical Ventilation

Eligibility

Sex: ALLMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with at least 10 days of mechanical ventilation at the intensive care unit of National Taiwan University Hospital and transferred to the Respiratory Care Center of National Taiwan University Hospital for weaning training * Patients who have undergone tracheostomy and still have a tracheotomy tube * Are at least 20 years old * Stable respiratory condition with inspired oxygen fraction not exceeding 50% Exclusion Criteria: * Hemodynamic instability or continuous use of vasopressors * Pregnancy

Locations (1)

National Taiwan University Hospital

Taipei, Taiwan

Outcomes

Primary Outcomes

Liberation from mechanical ventilation at discharge from the weaning unit

At least five consecutive days of free from mechanical ventilation ventilation

Time frame: Five days