Treatment of Ano-perineal Fistulas Resistant to Surgical Treatment with a Gel and Plug of Wharton's Jelly

Inclusion Criteria: * Male or female, aged 18 to 65 years. * Patient with a single anal fistula resistant after at least one surgical treatment. Fistula may be related to Crohn's disease. * Patient with an upper transsphincteric or lower transsphincteric fistula. * Patient presenting fistula with or without intersphincteric diverticula. * Fistula effectively drained with a seton. * Informed and consenting patient. * Patient who is a member or a beneficiary of a national health insurance plan. Exclusion Criteria: * Pregnant or breastfeeding woman or woman of childbearing age without effective contraception. * Patients who have had more than one failed obstruction technique. * Patient with more than one internal orifice. * Patient with an MRI proven abscess. * Patient with an uncontrolled infection. * Patient with a contraindication to anesthesia. * Person deprived of liberty by a judicial or administrative decision. * Adult subjected to a legal protection measure or unable to express his / her consent.