Primary Obstructive Megaureter Management in Eastern Interregional Area

University Hospital, Strasbourg, France120 enrolled

Overview

Congenital obstructive megaureter is a urinary malformation affecting the ureterovesical junction and causing obstruction to the flow of urine. It is the second most common cause of hydronephrosis. This malformation affects four times more boys than girls and is bilateral in 25% of cases. It is also associated with contralateral renal dysplasia in 15% of cases. The obstruction is linked to aperistalsis and hypertrophy of the circular muscle bundles and increased collagen 1 level. This malformation is accessible to antenatal screening from the second trimester. It falls within the scope of CAKUT and requires regular monitoring. Indeed, this uropathy can cause repeated pyelonephritis, kidney scarring and affected kidney function.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Congenital Obstructive Megaureter

Eligibility

Sex: ALLMin age: 1 YearMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Minor patient (from 1 to 17 years old) * Patient treated between January 2010 and December 2017 in one of the participating centers for an obstructive congenital mega-ureter * Subject (and/or his parental authority) not having expressed, after information, his opposition to the reuse of his data for the purposes of this research Exclusion Criteria: * Subject (and/or his parental authority) having expressed, after information, his opposition to the reuse of his data for the purposes of this research

Locations (1)

Outcomes

Primary Outcomes

Determine over the past seven years, the operability factors of patients aged 0 to 5 years regardless of the surgical technique used

This study aims to make a retrospective inventory and perspective on the management of congenital obstructive mega ureter

Time frame: Files analysed retrospectively from January 01, 2010 to December 31, 2017 will be examined