Breast cancer survivors aged 60+ and with overweight/obesity who had completed chemotherapy 1-6 years earlier completed 8 weeks of 12-8 pm weekday-only time-restricted eating. The intervention was delivered by a registered dietitian call, twice-daily automated text messages asking about eating start/stop times, and three support phone calls.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
22
Restriction of calorie intake to an 8-hour window, with water only fasting in the remaining 16 hours of the 24-hour period
Edmonton Clinic Health Academy
Edmonton, Alberta, Canada
Framingham 10-year cardiovascular risk score (%)
Calculated using the Canadian Cardiovascular scoring system
Time frame: 8 weeks
Visceral adipose tissue
measured via magnetic resonance fat-water separation imaging
Time frame: 8 weeks
Thigh adipose tissue fraction
Relative measure of amount of inter+intra muscular adipose tissue within the thigh muscle measured via magnetic resonance fat-water separation imaging
Time frame: 8 weeks
Liver adipose tissue fraction
Relative measure of amount of adipose tissue within the liver
Time frame: 8 weeks
Cardiorespiratory fitness
Measured as peak volume of oxygen consumed collected with a cycle erogmeter exercise test
Time frame: 8 weeks
Resting energy expenditure
Collected via metabolic cart in supine resting position after overnight fast
Time frame: 8 weeks
Respiratory quotient
Collected via metabolic cart in supine resting position after overnight fast
Time frame: 8 weeks
Lipid profile
Collected via analysis of fasting blood sample by Lifelabs commercial laboratory
Time frame: 8 weeks
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Hemoglobin A1c
Collected via analysis of blood sample by Lifelabs commercial laboratory
Time frame: 8 weeks
Waist circumference
measured as the average of two measurements to the nearest 0.5 cm.
Time frame: 8 weeks
Fasting glucose
Collected via analysis of fasting blood sample by Lifelabs commercial laboratory
Time frame: 8 weeks
Fasting insulin
Collected via analysis of fasting blood sample by Lifelabs commercial laboratory
Time frame: 8 weeks
Resting systolic and diastolic blood pressure
measured as the average of two measurements 60 seconds apart following 5-10 minutes of supine rest using an automated device
Time frame: 8 weeks
Body mass
measured by physicians scale after overnight fast
Time frame: 8 weeks
Whole-body fat mass
estimated using8-point bioelectric impedance (Seca)
Time frame: 8 weeks
Whole-body fat-free mass
estimated using8-point bioelectric impedance (Seca)
Time frame: 8 weeks