Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal Snapshot

Overview

APOLLO (Acute PresentatiOn of CoLorectaL Cancer: an internatiOnal snapshot) is an international, multi-centre, prospective observational study which will address this need and aims to describe the operative and non-operative management of emergency presentations of colon and rectal cancer in an international cohort.

Primary aim: Describe the variation in the operative and non-operative management of emergency presentations of colon and rectal cancer in an international cohort. Secondary aims: * Identify risk factors for mortality (intraoperatively, at 30-days and at 90-days) and ostomy rates (at 30- and 90-days) in patients deemed for active management (i.e., not for palliative management) to develop a risk prediction model * Validate risk criteria of large bowel obstruction in patients with previously known colorectal cancer undergoing neoadjuvant chemotherapy or awaiting elective surgery Who? * Patients aged 18 years and above presenting to the hospital acutely with colorectal cancer (CRC) for malignant large bowel obstruction (LBO), perforation, CRC-related haemorrhage or other reasons within the data collection periods. Both those managed with and without surgery will be included * Patients with localised and metastatic disease will be included * Patients with known colorectal cancer diagnoses will be included if they present acutely (e.g., with disease progression) * Patients presenting acutely for the side effects of chemotherapy/radiotherapy of known cancers will be excluded What? Data will be collected on patients' presenting status and symptoms, patient management strategies, and intraoperative and postoperative outcomes. When? Prospectively over 2023 in consecutive 6-week data collection blocks between January and June with 90-day follow-up till September.

Conditions

Eligibility

Locations (1)

Outcomes