Observational Study of Exposure to Environmental Toxicants Among Firefighters

Masonic Cancer Center, University of Minnesota60 enrolled

Overview

Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy

Interventions

Sample collectionOTHER

This study will involve three sample collections including buccal cells and urine samples

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Firefighter (career or volunteer) * Over 18 years of age * Able to provide written voluntary consent Exclusion Criteria: * Unwilling to provide a pre and post-exposure urine sample * Current cancer diagnosis * Tobacco use within the last 1 year (verified by urinary TNEs)

Locations (1)

Masonic Cancer Center

Minneapolis, Minnesota, United States

RECRUITING

Outcomes

Primary Outcomes

Studying biomarker levels in firefighters pre and post fire call.

The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.

Time frame: 48 months

Central Contacts

Joni Jensen

CONTACT

612-624-5178 jense010@umn.edu

Data from ClinicalTrials.gov

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