This study is a multicenter, prospective, cohort study to observe the clinical efficacy and safety of edaravone dextrol in patients with acute ischemic stroke in a real-world setting.
The study lasts a total of 90 days and includes three phases: screening, treatment, and follow-up. Treatment period: patients are divided into exposure group and non-exposed group based on the use of edaravone dextrol after ischemic stroke. The exposure group: edaravone dextrol is used according to reference to clinical practice, without specific restrictions. The non-exposed group: edaravone dextrol is not used, and concomitant therapy is at the clinician's discretion. Follow-up period: All patients continue to be followed up to 90 days after stroke onset.
Study Type
OBSERVATIONAL
Enrollment
4,750
intravenous edaravone dexborneol 37.5mg twice daily
Junwei Hao
Beijing, China
RECRUITINGProportion of patients with modified Rankin Scale (mRS) score 0-1
Proportion of patients with modified Rankin Scale (mRS) score (on a scale from 0 to 6, with higher scores indicating greater disability) of 0 to 1 at 90±7 days
Time frame: 90±7 days
Proportion of patients with mRS 0-2
Proportion of patients with mRS score of 0 to 2 at 90±7 days
Time frame: 90±7 days
Distribution of mRS score
Distribution of mRS score at 90±7 days
Time frame: 90±7 days
Neurological functional change
The change of NIHSS score at discharge compared with the baseline NIHSS score
Time frame: at discharge, an average of 7 days
Quality of Life (EQ-5D-5L) at 90 days
The value of EQ-5D-5L at 90±7 days
Time frame: 90±7 days
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