The purpose of this study is to implement a prehabilitation intervention to enhance recovery for people undergoing allogeneic stem cell transplant for hematologic malignancies. All participants in this study will receive a prehabilation intervention in addition to usual care (no change to their chemotherapy protocols or transplant) and several quality of life and fitness scores will be measured throughout the intervention.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
60
A multiphasic exercise prehabilitation program for alloHSCT candidates across each treatment phase, that includes behaviour change support
Feasibility of Implementing an Exercise Program for Patients Undergoing Allogeneic-HSCT, Measured by Participant Attendance
Review participant attendance/participation in the program and the questionnaires.
Time frame: 6-9 months
Amount of Physical Activity Measured With Activity Tracker
Quantity of physical activity, measured in hours.
Time frame: 6-9 months
Exercise Behaviour Measured with Modified Godin Leisure Time Exercise Questionnaire
Self reported measure of physical activity. Higher scores are better.
Time frame: 6-9 months
Patient Quality of Life Measured with the Functional Assessment of Cancer Therapy-Bone Marrow Transplant and EuroQol 5 Dimension 5 Level Questionnaire
Self reported physical, emotional and functional well-being.
Time frame: 6-9 months
Level of Fatigue Measured with the Functional Assessment of Chronic Illness Therapy Fatigue Scale (FACIT-F) Questionnaire
Self reported level of fatigue during daily activities. Lower scores mean less fatigue.
Time frame: 6-9 months
Amount of Anxiety and depression Measured with the Hospital Anxiety and Depression Scale (HADS) Questionnaire
Self reported level of anxiety and depression. Higher scores indicate more anxiety and depression.
Time frame: 6-9 months
Amount of Symptom burden Measured with the Edmonton Symptom Assessment System-revised (ESAS-r) Questionnaire
Self reported symptoms. Higher scores indicate more symptoms.
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Time frame: 6-9 months
Patient's Performance Status Measured by the Eastern Cooperative Oncology Group (ECOG) Scale
Objective score of patient's level of functioning. Lower scores indicate better functioning.
Time frame: 6-9 months
Handgrip Strength Measured by Handgrip Dynamometry
Maximum isometric strength of the hand and forearm muscles.
Time frame: 6-9 months
Balance Measured by Single Leg Stance Test
Static postural and balance control, measured in seconds.
Time frame: 6-9 months
Lower Limb Muscular Endurance Measured with 30-second sit-to-stand Test
Tests leg strength and endurance, measured in number of stands in 30 seconds.
Time frame: 6-9 months