Tradipitant for Functional Dyspepsia

Phase 2Enrolling By InvitationNCT05653310

Xiao Jing (Iris) Wang60 enrolled

Overview

To evaluate the effects of tradipitant relative to placebo on gastric motor functions, satiation, and postprandial symptoms in patients with functional dyspepsia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Functional Dyspepsia

Interventions

TradipitantDRUG

Tradipitant Capsule

PlaceboDRUG

Placebo Capsule

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Able to provide written consent * Body Mass Index (BMI) of 18-35 kg/m2 * Absence of other diseases which could interfere with interpretation of study results Exclusion Criteria: * Current H. pylori infection * Pregnancy or nursing * Recent history of Alcohol Use Disorder or Substance Use Disorder

Locations (1)

Mayo Clinic in Minnesota

Rochester, Minnesota, United States

Outcomes

Primary Outcomes

Accommodation gastric volumes measured by single photon emission computed tomography (SPECT)

Time frame: 4 Weeks

Data from ClinicalTrials.gov

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