The purpose of the study is to evaluate the relationship between perioperative electroencephalogram and emergence agitation in the nasal surgery. Previous studies showed that low frequency band wave activity increased during emergence delirium in pediatric patients. It is still not enough to explain the relationship between emergence agitation and electroencephalogram in adults. Researchers will demonstrate the relationship between parameters related electroencephalogram and emergence agitation in adults undergoing nasal surgery.
Researchers use Sedline to perform perioperative EEG measurements of young adult patients undergoing nasal surgery under general anesthesia with sevoflurane. Emergence agitation occurrence and EEG patterns are observed. The researchers record the patient's sex, type of surgery, pre-education on emergence agitation, preoperative hospital anxiety and depression scale (HADS), postoperative pain, amount of analgesics administered in the surgery/recovery room, and PACU time. Investigators check the correlation between EEG and perioperative variables. Investigators also compare EEG and perioperative variables for those who were given an explanation of emergence agitation and those who were not.
Study Type
OBSERVATIONAL
Enrollment
55
Nasal surgery under general anesthesia using inhalational agent (sevoflurane)
Gangnam Severance Hospital Yonsei University College of Medicine
Seoul, South Korea
RECRUITINGEEG band relative power measured in the frontal lobe
relative power of each brain waves : Original frontal EEG waves using 4 channel sedline (Masimo, Irvine, CA, USA) sensor will processed by FFT(fast Fourier transform). Each band is as follows.: Delta: 1-4 Hz Theta: 4-8 Hz Alpha: 8-13 Hz Beta: 13-30 Hz.
Time frame: From the cessation of sevoflurane inhalation to the extubation of tracheal tubes
occurrence of emergence agitation
Emergence agitation occurrence : RASS(Richmond Agitation Sedation Score) is 10 scaled (-5\~+4) score to assess sedation/agitation level; 0 is a calm state, and a value less than 0 means a sedation state.
Time frame: From the cessation of sevoflurane inhalation to transfer to the recovery room
HADS (Hospital Anxiety and Depression Scale)
A self-assessment scale, brief, clinically useful measure of anxiety and depression symptoms. It can be used to diagnose depression in people with significant physical ill-health.
Time frame: 1 day before surgery (after admission)
VAS (Visual Analogue Scale)
Using a ruler, it is 11 scaled (0-10) score to assess pain.
Time frame: during 30 minutes after PACU admission
Effect of preoperative education on emergence agitation
Investigate the relationship between preoperative emergence agitation explanation and occurrence of emergence agitation
Time frame: up to 6 months after completion of the study
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