Adequate pain management following total hip arthroplasty (THA) is a key component for patient satisfaction and early ambulation. However, due to the complexity of the innervation of the hip joint, the most appropriate anaesthetic and analgesic technique for THA remains unclear. A femoral nerve block is commonly performed and well established but is associated with motor weakness. Recently, the pericapsular nerve group (PENG) block has been introduced as an effective choice which targets the articular branches of the hip. The quadratus lumborum block (QLB) is a relatively new regional block that has been reported to provide effective analgesia for THA. The main objective of this study is to compare the effectiveness of the ultrasound-guided PENG block technique compared to QLB block in terms of efficacy of pain control and the safety profile after total hip arthroplasty under spinal anesthesia.
The patients will be randomly classified into two equal groups (40 patients each). Group allocation will be done by computer generated random numbers and closed opaque sealed envelopes. The study will be designed to be double blind as all patients and outcomes assessor will be blinded to group assignment. Patients will be randomized to one of three equal groups: Group I (n= 40 patients): Patients in this group will receive an ipsilateral single shot of QLB (30 ml of plain bupivacaine 0.25%) after surgery using ultrasonographic guidance. Group II(n= 40 patients): patients in this group will receive an ipsilateral single-shot of PENG block (25 ml of plain bupivacaine 0.25%) and LFCN block (5 ml of plain bupivacaine 0.25%) after surgery using ultrasonographic guidance.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
Bupivacaine 0.25% injection
Alper KILICASLAN
Konya, Turkey (Türkiye)
Pain scores
Numerical Rating Scale-NRS (0 = no pain and 10 = worst imaginable painranged from 0 to 10)
Time frame: Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours
Opioid consumption
Mean opioid consumption in morphine equivalents
Time frame: Changes from baseline opioid consumption at postoperative 0, 2, 6, 12 and 24 hours
Quadriceps muscle strength
Quadriceps motor function will be tested with the patient supine and with the hip and knee flexed at 45º and 90º, respectively
Time frame: Postoperative 24 hours period
Presence of postoperative nausea, vomiting, pruritus, urinary retention, respiratory depression
Presence of postoperative nausea, vomiting, pruritus, urinary retention, respiratory depressio
Time frame: Postoperative 24 hours period
Patient satisfaction
Patients asked whether they would choose the same anaesthetic management in a future operation: Yes/No
Time frame: Postoperative 24 hours period
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