The investigators will include patients suffering from Major Depressive Disorder (MDD), in episode. The patients will undertake neuropsychological tasks evaluating executive function and clinical assessment related to depressive symptoms, anxiety, transdiagnostic symptoms and psychological skills.
The investigators will include patients suffering from MDD, in episode. The patients will be evaluated with the MINI-7 interview. Then, the participants will undertake different neuropsychological tasks evaluating executive function: the stroop task, the D2 tasks, the finger tapping test and the mindpulse. The participants will also undertake clinical evaluation the MADRS, the Transdiagnostic Skills Scale, the Symptomatic Transdiagnostic Test, the STAI and the Severity Insomnia Indexes. The investigators will perform correlational analysis between the neuropsychological tasks and the clinical evaluations. The investigators will also compare the predictive power of the different neuropsychological tasks on depressive symptoms.
Study Type
OBSERVATIONAL
Enrollment
80
In practice, this tool measures the speed at which an individual reacts to the appearance of a simple image on a screen with instructions to react only to certain images. It thus makes it possible to measure the speed of information processing, attention, executive functions and reaction to difficulty
Clinique psychiatrique universitaire
Tours, France
MADRS score
The severity of the depression will be assessed using the MADRS score. Montgomery-Asberg Depression Scale (MADRS) The scale has 10 items rated from 0 to 6. 0 to 6 points: the patient is considered healthy. 7 to 19 points: the patient is considered to be in mild depression. 20 to 34 points: the patient is considered to be in moderate depression. \> 34 points: the patient is considered to be in severe depression.
Time frame: baseline
Simple reaction time (SRT) obtained at the MindPulse test
The "simple reaction time" (SRT) is the reaction time to the first test (the subject releases the mouse click as quickly as possible when an image appears) , it contains the time needed to perceive and analyse the image, to formulate the response and to execute the motor response.
Time frame: Baseline
Go/NoGo score obtained at the MindPulse test
reaction time with a categorisation where the subject must react or not react (Go/NoGo) according to the categorical target, in this case a light or dark colour (white coloured image or grey coloured image).
Time frame: Baseline
Executive speed (ES) obtained at the MindPulse test
The ES Score corresponds to the Executive Speed, i.e. the average time of categorisation of the subject.
Time frame: Baseline
Reaction to difficulty obtained at the MindPulse test
It corresponds to the adaptation of the subject to the level of difficulty. The shift of the circle above the blue rectangle indicates a higher than expected slowing down in reaction to the difficulty of the instruction, while a shift below the blue rectangle indicates that the participant is not slowing down enough in response to the difficulty and is at risk of making mistakes.
Time frame: Baseline
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Level of anxiety
measured by a self-questionnaire : State Trait Anxiety Inventory (STAI) 40 items rated from 1 to 4
Time frame: Baseline
clinical characterisation
Measured by a scale : Transdiagnostic Skills Scale (T2S) 42 items rated from 1 to 7
Time frame: Baseline
clinical characterisation
Measured by a questionnaire : Transdiagnostic Evaluation Scale (ETE) 66 items rated from 1 to 7
Time frame: Baseline
insomnia severity
Measured by an insomnia severity index (ISI) 5 items rated from 0 to 4
Time frame: Baseline
Stroop test
standardised cognitive assessment is measured by neuropsycological tests as stroop test
Time frame: Baseline
D2R
standardised cognitive assessment is measured by neuropsycological tests as D2R test that measures the concentration
Time frame: Baseline
Finger tapping test
standardised cognitive assessment is measured by neuropsycological tests as Finger tapping test rated from 0 to 4
Time frame: Baseline