The purpose was to assess knee function outcomes between physical therapy and arthroscopic partial menisectomy(APM) for Metabolic syndrome(MetS) patients with degenerative meniscus lesions(DMLs) during 12 month follow up.
Metabolic syndrome were diagnosed with abdominal obesity, insulin resistance with or without glucose intolerance, dyslipidemia or elevated blood pressure and widely prevalence all around the world.MetS patients were always correlated with knee osteoarthritis or cartilage volume loss. For MetS patients with DMLs, whether physical therapy was non-inferior to APM in knee function and MetS components was unknown.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
120
The exercise intervention included aerobic exercises and resistance exercise, flexibility exercises about 150 minutes for ≥2 day per week.
Arthroscopic partial meniscectomy surgery procedure
Shenzhen People's Hospital
Shenzhen, Guangdong, China
RECRUITINGthe Knee Injury and Osteoarthritis Outcome Score (KOOS) change
The Knee injury and Osteoarthritis Outcome Score (KOOS) holds five subscales including: Pain (9 items); other Symptoms (7 items); Activities of Daily Living (ADL, 17 items); Sport and Recreation function (Sport/Rec, 5 items); and knee-related Quality of Life (QoL, 4 items). Each subscale is scored separately from zero (extreme knee problems) to 100 (no knee problems)
Time frame: change from baseline up to 12 months
the International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC Score) change
The International Knee Documentation Committee Subjective Knee Evaluation Form (IKDC) score questionnaire contains 18 items (7 items for symptoms, 1 item for sport activity, 9 items for daily activities, and 1 item for current knee function.) The total score is transformed to a value on a scale of 0 to 100, with 100 representing the highest knee function and 0 is the worst.
Time frame: change from baseline up to 12 months
waist circumstance change
waist circumstance (cm)
Time frame: change from baseline up to 12 months
systolic blood pressure change
systolic blood pressure /mmHg
Time frame: change from baseline up to 12 months
diastolic blood pressure change
diastolic blood pressure/mmHg
Time frame: change from baseline up to 12 months
serum total cholesterol (TC) change
serum total cholesterol (TC) (mmol/L)
Time frame: change from baseline up to 12 months
serum triglycerides (TG) change
serum triglycerides (TG) (mmol/L)
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Time frame: change from baseline up to 12 months
low-density lipoprotein cholesterol (LDL-C) change
serum low-density lipoprotein cholesterol (LDL-C) (mmol/L)
Time frame: change from baseline up to 12 months
high-density lipoprotein cholesterol (HDL-C) change
serum high-density lipoprotein cholesterol (HDL-C) (mmol/L)
Time frame: change from baseline up to 12 months
fast blood glucose(FBG) change
serum fast blood glucose(FBG) (mmol/L)
Time frame: change from baseline up to 12 months
Body mass index change
Body mass index(BMI) weight/height square (kg/㎡)
Time frame: change from baseline up to 12 months
Kellgren-Lawrence (K/L) grade change
Kellgren-Lawrence (K/L) grade
Time frame: change from baseline up to 12 months
pain score change
The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula.
Time frame: change from baseline up to 12 months
symptoms score change
The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula.
Time frame: change from baseline up to 12 months
activities of daily living score change
The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula
Time frame: change from baseline up to 12 months
function in sport and recreation score change
The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula
Time frame: change from baseline up to 12 months
knee related quality of life score change
The minimum is 0 points, the maximum is 4 points, from extreme knee problems to no knee problems. After the score of each part is calculated separately, it is converted into a percentage score by the conversion formula
Time frame: change from baseline up to 12 months