Correlation of Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome

Cairo University100 enrolled

Overview

We designed a study to determine if ovarian volume (OV) and/or follicle number (FN) are independently associated with abnormal metabolic findings in women diagnosed with PCOS. We hypothesized that ovarian morphology but not follicle number would be associated with a significantly higher odds of hyperinsulinemia among women with PCOS.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Study the Relationship Between Insulin Resistance With Hormonal and Ovarian Morphological Characteristics in Patients With Polycystic Ovarian Syndrome

Interventions

No interventionOTHER

We try to find an association between insulin resistance with ovarian hormonal and morphological characteristics in patients with polycystic ovarian syndrome

Eligibility

Sex: FEMALEMin age: 16 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: A-patients met the Rotterdam criteria of PCO with two out of three of the following: 1. oligo-or-anovulation 2. clinical and/or biochemical hyperandrogenism 3. the presence of 10 or more antral follicles in one ovary and/or a maximum ovarian volume \> 10cc B-reproductive age group (16:45 years) C-BMI \<40 Exclusion Criteria: A-age \>40 years B-BMI\>40 C-previous ovarian surgery D-chronic medical disorders \[DM , HTN , ...\]