In the present study, the investigators use high-resolution MR vessel wall imaging, and select patients with cerebral and cervical artery occlusion to investigate the relationship between the imaging appearance of thrombus and the various outcome of recanalization treatment.
Cerebral ischemic stroke resulting from thrombosis causes high disability and mortality. There are few biomarkers to evaluate arterial thrombophilia until now. Previous studies have demonstrated that atherosclerotic plaque rupture and erosion are major etiologies initiating thrombosis. Based on previous works targeting the role of plaque and blood flow in cerebrovascular disease, in the present study, the investigators use high-resolution MR vessel wall imaging, and select patients with cerebral and cervical artery occlusion to explore the relationship between the imaging appearance of thrombus and the various outcome of recanalization treatment. The study's objective was to solve the challenges in the mechanism of thrombus features and the outcome of recanalization therapy, thus helping improve the primary and secondary prevention of cerebrovascular disease.
Study Type
OBSERVATIONAL
Enrollment
100
Imaging appearance of intracranial and/or extracranial arterial thrombus
Chinese PLA General Hospital
Beijing, Beijing Municipality, China
RECRUITINGRate of Successful Recanalization
Antegrade blood flow through the recanalized portion was assessed by thrombolysis in myocardial infarction (TIMI) score or thrombolysis in cerebral infarction (TICI) score. TIMI≥2 or TICI≥2b was defined as successful recanalization.
Time frame: 1-3 Years
Ischemic Stroke Occurrence
Ischemic stroke occurrence during follow-up period which was confirmed by neuroimaging
Time frame: 1-3 Years
Number of Participants with Adverse Events
hemorrhagic or ischemic stroke after recanalization treatment
Time frame: 1-3 Years
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