This observational and retrospective study will follow the recommendations of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE). The aim is to verify and analyze the clinical and laboratory variables with prediction capability for indication of invasive ventilatory support in patients with COVID-19. The present study will be carried out in specific care units for patients with suspected or confirmed COVID-19. Individuals with suspected or clinical diagnosis of COVID-19, with a minimum hospital stay of 24 hours and submitted to oxygen therapy or non-invasive ventilation will be selected. Clinical and laboratory variables will be collected from the moment of admission and every 12 hours until the third day of hospitalization. The primary outcome will be rate of endotracheal intubation, while secondary outocomes will be lenght of stay in intensive care unit, and hospital, as well as mortality rate.
Clinical and laboratory data will be collected from medical records from the period of the COVID-19 pandemic (February 2020 to June 2021)
Study Type
OBSERVATIONAL
Enrollment
350
Clinical and laboratory data will be collected from patients who are intubated after 48 hours of admission to the intensive care unit
Pedro Ernesto University Hospital
Rio de Janeiro, Brazil
National Institute of Infectology Evandro Chagas
Rio de Janeiro, Brazil
Clementino Fraga Filho University Hospital
Rio de Janeiro, Brazil
Identify clinical and laboratory variables that may be associated with the need of endotracheal intubation in the first 72 hours of admission to the intensive care unit.
Vital signs will be collected through the cardiac monitor and clinical evaluation from the moment of admission until the third day of hospitalization, every twelve hours and full blood count and biochemistry data will be collected from patients at admission until the third day of hospitalization in the intensive care unit
Time frame: 3 days
time to endotracheal intubation
It will be collected from the date of intensive care unit admission until the date of endotracheal intubation
Time frame: 28 days
length of stay in the ICU
It will be collected from the date of intensive care unit admission until the outcome of discharge from the intensive care unit or death.
Time frame: 6 months
length of hospital
It will be collected from the date of intensive care unit admission until the outcome of hospital discharge or death.
Time frame: 12 months
mechanical ventilation days
It will be collected from the date of intubation in the intensive care unit until the date of extubation or up to 48 hours off mechanical ventilation in cases of tracheostomized patients and/or until the outcome of death
Time frame: 6 months
hospital mortality
Mortality will be collected during the period of hospitalization
Time frame: 12 months
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