Main Purpose: To evaluate the effect of photodynamic therapy on soft tissue healing after tooth extraction at periodontal infection site, and to compare the effect on pain degree and bone tissue remodeling after tooth extraction.
The aim of this study is to evaluate the effect of photodynamic therapy (PDT) on soft tissue healing and bone remodeling in tooth extraction sockets after tooth extraction. The enrolled patients will be randomized into two groups. The control group used conventional tooth extraction to clean the wound, and the experimental group used photodynamic therapy to help clean the wound. Seven days and 14 days after extraction, the area of extraction socket was measured, the healing rate of extraction socket was calculated, and Landry, Turnbull and Howley soft tissue healing index was measured. The degree of pain was recorded at 6h, 1 day, 2 days and 3 days after tooth extraction. Bone remodeling indexes were measured at 1 month after tooth extraction.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
38
The tooth extraction sockets were filled with photosensitizer methylene blue. The guide head of the laser periodontal therapy instrument (Dental diode laser device Paiwei™(Zhengzhou Gata biotechnology Co.,Ltd.,China) which was 650-670nm with a power of 160mw-220mw.) was placed in the tooth extraction sockets to probe and move around the tooth extraction sockets for 1 minute. At the end of irradiation, a cotton ball dipped in saline was used to wipe the guide head and rinse the photosensitizer out of the socket
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Wound healing rate at 7 days
(The size of the tooth extraction wound area at 7 days)/(The size of the tooth extraction wound area at baseline)
Time frame: baseline;at 7 days
Landry, Turnbull and Howley soft tissue healing index
Soft tissue index of healing wound after tooth extraction
Time frame: baseline, at 7 days; at 14days
Degree of pain
VAS score was used to evaluate the pain degree of tooth extraction trauma. A score of 0 indicates no pain and a score of 10 indicates severe pain.
Time frame: at 6 hours; at 1 day; at 2 days; at 3 days
Changes in Bone Mineral density
Changes in Bone Mineral density
Time frame: baseline, at 1 month
Bone height changes
Bone height changes
Time frame: baseline, at 1 month
Wound healing rate at 14 days
(The size of the tooth extraction wound area at 14 days)/(The size of the tooth extraction wound area at baseline)
Time frame: baseline;at 14 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.