The primary objectives of this study are to increase HPV vaccination initiation and 3-dose completion among pediatric, adolescent, and young adult (PAYA) cancer survivors
PAYA cancer survivors are 2.8 times more likely to develop a secondary human papillomavirus (HPV)-associated cancer than the general population. Unfortunately, HPV vaccination coverage among PAYA cancer survivors is even lower than that in the general population. Provision of adequate vaccine information and instructions for timing of vaccination post-treatment is associated with an increased intention to vaccinate. Nonetheless, research show a minority of cancer care teams specifically discuss HPV vaccination with PAYA cancer survivors and their caregivers. The purpose of this study is to test the efficacy of an oncologist- and clinic-level intervention and the additional effect of a patient-level app-based intervention to improve initiation and 3-dose completion of the HPV vaccine series.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Enrollment
162
Game-based Learning Avatar-navigated mobile (app) provides information on HPV infection susceptibility, risk of HPV-associated cancers, screening methods, and ways to overcome screening barriers. Users navigate the app using an avatar, and earn points for game components completed. The app prompts screening using text message reminders based on patient-entered information, and links to schedule cervical cancer screening. Completing cervical cancer screening earns an electronic badge visible to other users via an anonymous screen name and avatar.
University of Minnesota Masonic Cancer Center
Minneapolis, Minnesota, United States
Study enrollment
Number of participants who complete the 3-dose HPV vaccine series within 12 months of study enrollment.
Time frame: within 6 months of index clinic visit
Change in HPV and HPV vaccination knowledge pre- and post-intervention
The change in knowledge is assessed through self reported surveys administered to participants
Time frame: baseline and 1 year post survivorship clinic visit
Number of participants intent to vaccinate against HPV
The number of participants with intent to vaccinate is assessed through self reported surveys administered to participants
Time frame: At the time of index clinic visit, baseline
Proportion of participants intending to vaccinate initiating and completing the vaccine series
The Proportion of participants intending to vaccinate initiating and completing the vaccine series is measured through surveys and health record review
Time frame: 1 year post index clinic visit
Demographics differences associated with vaccination status
measure through health record review
Time frame: 1 year post index clinic visit
Cancer occurrences associated with vaccination status
measure through health record review
Time frame: 1 year post index clinic visit
Treatment differences associated with vaccination status
measure through health record review
Time frame: 1 year post index clinic visit
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Number of participants experiencing barriers to vaccination
Survey measurement
Time frame: 1 year post index clinic visit
Number of participants using and accepting the game based learning app
Survey measurement
Time frame: 1 year post index clinic visit
Concordance between reported and documented vaccination against HPV
measured through surveys and health record review
Time frame: 1 year post index clinic visit