In this study, the investigator will evaluate the rate of reversal of complete heart block with aminophylline in atropine resistant patients with inferior wall myocardial infarction (MI)
Administration of Aminophylline can result in reversal of complete heart block in a significant number of atropine resistant patients with inferior wall MI. Hence, in this study our primary aim is to evaluate the rate of reversal of complete heart block with aminophylline in atropine resistant patients with inferior wall MI.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Injection Aminophylline IV 240 mg will be given over 10 minutes. After 1 hour, Aminophylline 240 mg second dose will be given over 10 minutes.
Reversal of complete heart block
Conversion to sinus rhythm with 1:1 conduction
Time frame: Within 1 hour of 2nd dose
Improved conduction
Combined end point of 1:1 conduction and improved conduction to second degree AV block
Time frame: Within 1 hour of 2nd dose
Major adverse cardiac events (MACE)
Ventricular arrhythmias ( VT more than 3 beats), decrease in ventricular escape rate requiring increasing pacing rate, cardiac arrest or death
Time frame: Within 12 hours
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