Research on Innovative Diagnosis and Treatment System of Syndrome Differentiation of Zang-fu Viscera and Effectiveness Evaluation Based on Inter-Arm Blood Pressure Measured Simultaneously

Inclusion Criteria: Case inclusion Criteria: * Patients were treated with epigastric pain and / or insomnia, which met the above diagnostic criteria for diseases, liver and spleen; * diagnostic criteria for diseases, liver and spleen; * Age 18-65 years old; * It can combine mild and moderate depression, anxiety Sign the informed consent form. Healthy control inclusion criteria: * PSQI \< 5 points; * No hypertension, diabetes, hyperlipidemia, coronary heart disease and other underlying diseases; * No depression, anxiety, malignant tumor, syphilis, HIV and other infectious diseases; * Over 18 years of age; * Volunteer to participate in this study, cooperate with the measurement of blood pressure in both arms, and sign the informed consent. Exclusion Criteria: Case exclusion criteria: * Patients with insomnia disorder caused by uneffectively controlled or serious diseases, such as malignant tumor, persistent pain, cardiovascular and cerebrovascular diseases, endocrine diseases, etc.; * patients with severe depression and mental illness; * Pregnant and lactation patients. Healthy controls exclusion criteria: * sleep apnea syndrome or restless leg syndrome and other sleep disorders; * Pregnant and lactation; * Abnormal symptoms and abnormal tongue pulse occur in the body, such as facial acne, dysmenorrhea, thick and greasy tongue coating, loose stools, fat tongue, teeth marks and tongue.