Hemodynamic Comparison of Peripheral and Central VA ECMO.

First Affiliated Hospital Xi'an Jiaotong University136 enrolled

Overview

The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO. The main question it aims to answer is: * Efficacy of the different cannulation strategies for the establishment of for VA-ECMO circulation on hemodynamics and organ perfusion. Participants require VA ECMO support, will be divided into two groups in an intention-to-treat analysis: central artery cannulation and peripheral artery cannulation. Researchers will analyze different cannulation strategies for VA-ECMO and identify potential advantages and disadvantages for two groups of VA-ECMO.

Study Type

OBSERVATIONAL

Enrollment

136

Conditions

Shock, Cardiogenic Cardiac Arrest Extracorporeal Circulation; Complications Hemodynamics Instability

Interventions

Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is mainly used for circulatory support in patients with severe cardiopulmonary failure. VA ECMO drains the blood from the venous system followed pumping the blood back into the arterial vascular compartment after oxygenation. It can be divided into two cannulation strategies for VA ECMO support, namely peripheral VA ECMO and central VA ECMO based on the arterial cannulation site. Peripheral VA ECMO is established via the femoral artery (FA), whereas axillary artery (AX) is an arterial cannulation site in central VA-ECMO.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age≥18 years * Participants with cardiogenic shock * Obtaining informed consent from participants or their affiliated beneficiaries Exclusion Criteria: * Irreversible heart failure * Contraindications to anticoagulation therapy * Uncontrolled bleeding * Irreversible neurological pathology * Participants limited to extracorporeal cardiopulmonary resuscitation