The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise capacities. The aim of this study was to evaluate respiratory muscle strength, functional exercise capacity, and diaphragmatic thickness in groups that underwent lobectomy with standard thoracotomy, muscle sparing thoracotomy, and video-assisted thoracic surgery (VATS).
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise capacities. The aim of this study was to evaluate respiratory muscle strength, functional exercise capacity, and diaphragmatic thickness in groups that underwent lobectomy with standard thoracotomy, muscle sparing thoracotomy, and video-assisted thoracic surgery (VATS). In this study we will evaluate respiratory muscle strength, functional exercise capacity, diaphragmatic thickness, postoperative pulmonary complications, pain, dyspnea, pulmonary function, functional status, anxiety and depression.
Study Type
OBSERVATIONAL
Enrollment
42
Hacettepe University
Ankara, Turkey (Türkiye)
Respiratory muscle strength (inspiration) change
Respiratory muscle strength will measure by measuring mouth pressure and using maximal inspiratory pressure (MIP) values. Preoperative and postoperative value differences will be calculated.
Time frame: The day before the operation.
Respiratory muscle strength (inspiration) change
Respiratory muscle strength will measure by measuring mouth pressure and using maximal inspiratory pressure (MIP) values. Preoperative and postoperative value differences will be calculated.
Time frame: 15-20 days after discharge.
Respiratory muscle strength (expiration) change
Respiratory muscle strength will measure by measuring mouth pressure and using maximal expiratory pressure (MEP) values. Preoperative and postoperative value differences will be calculated.
Time frame: The day before the operation.
Respiratory muscle strength (expiration) change
Respiratory muscle strength will measure by measuring mouth pressure and using maximal expiratory pressure (MEP) values. Preoperative and postoperative value differences will be calculated.
Time frame: 15-20 days after discharge.
Functional exercise capacity
6-minute walk test (6MWT) will be used to evaluate functional exercise capacity.
Time frame: The day before the operation.
Functional exercise capacity
6-minute walk test (6MWT) will be used to evaluate functional exercise capacity.
Time frame: 15-20 days after discharge.
Diaphragmatic thickness
Ultrasound will be used to measure diaphragmatic thickness.
Time frame: The day before the operation.
Diaphragmatic thickness
Ultrasound will be used to measure diaphragmatic thickness.
Time frame: 15-20 days after discharge.
Postoperative Pulmonary Complication
Postoperative pulmonary complications will be evaulate by Melbourne Group Scale. If more than 4 parameters are positive, it will be considered as having postoperative pulmonary complication.
Time frame: Postoperative first-fifth days.
Postoperative pain
Visual anolog scala will be used to measure pain. Zero is considered as no pain an ten s considered as no maximal pain.
Time frame: The operative day after the operation.
Postoperative pain
Visual anolog scala will be used to measure pain. Zero is considered as no pain an ten s considered as no maximal pain.
Time frame: Postoperative first-fifth days.
Postoperative pain
Visual anolog scala will be used to measure pain. Zero is considered as no pain an ten s considered as no maximal pain.
Time frame: 15-20 days after discharge.
Dyspnea
Dyspnea will be evaulate by Modifiye Medical Research Council Dyspnea Scale (mMRC).
Time frame: The day before the operation.
Dyspnea
Dyspnea will be evaulate by Modifiye Medical Research Council Dyspnea Scale (mMRC).
Time frame: 15-20 days after discharge.
Pulmonary function (FEV1)
Pulmonary function will be evaulate by pulmonary function test. FEV1 will be measured in liter.
Time frame: The day before the operation.
Pulmonary function (FEV1)
Pulmonary function will be evaulate by pulmonary function test. FEV1 will be measured in liter.
Time frame: 15-20 days after discharge.
Pulmonary function (FVC)
Pulmonary function will be evaulate by pulmonary function test. FVC will be measured in liter.
Time frame: The day before the operation.
Pulmonary function (FVC)
Pulmonary function will be evaulate by pulmonary function test. FVC will be measured in liter.
Time frame: 15-20 days after discharge.
Pulmonary function (FEF25-75)
Pulmonary function will be evaulate by pulmonary function test. FEF25-75 will be measured in liter.
Time frame: The day before the operation.
Pulmonary function (FEF25-75)
Pulmonary function will be evaulate by pulmonary function test. FEF25-75 will be measured in liter.
Time frame: 15-20 days after discharge.
Pulmonary function (PEF)
Pulmonary function will be evaulate by pulmonary function test. PEF will be measured in liter.
Time frame: The day before the operation.
Pulmonary function (PEF)
Pulmonary function will be evaulate by pulmonary function test. PEF will be measured in liter.
Time frame: 15-20 days after discharge.
Functional Status
Karnofsky Performance Status Scale will be used to evaluate functional status. It will be used i to assess the preoperative condition.
Time frame: The day before the operation.
Anxiety and Depression
Anxiety and depression will be evaulate by Hospital Anxiety and Depression Scale. 7 of the survey questions question depression and 7 of them question anxiety.
Time frame: Postoperative first-fifth days.
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