The aim of the study is to evaluate the safety and efficacy of diosmin as adjuvant therapy in treatment of non-bleeding peptic ulcer patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
44
diosmin 500 mg twice daily
Tanta University
Tanta, El Gharbia, Egypt
RECRUITINGassesment of improvement of symptoms as indicated by change in SAGIS scale.
patients will undergo clinical assessment according to SAGIS scale at baseline and 2 months
Time frame: 2 months
change in Malondialdehyde (MDA) serum levels.
blood samples will be collected at baseline and 2 months.
Time frame: 2 months
change in Prostaglandin E2 (PGE2) serum levels.
blood samples will be collected at baseline and 2 months.
Time frame: 2 months.
change in Endothelin-1 (ET-1) serum levels.
blood samples will be collected at baseline and 2 months.
Time frame: 2 months
change in b-cell lymphoma 2(bcl-2) serum levels.
blood samples will be collected at baseline and 2 months.
Time frame: 2 months
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