The goal of this clinical trial is to study the efficacy of collagen supplement on the moisture content and elasticity. 70 participants of 30-50 years old women will be enrolled from two study sites and randomly assigned to use two products (study product plus collagen supplement and placebo product without collagen supplement) for 2 months. Researchers will compare the two groups to validate the assumption that there is significant improvement on skin anti-aging effect for participants using study product plus collagen supplement.
This study is two arms, randomized, double-blind controlled trial. There will be two study sites and 35 eligible participants at each study site will be enrolled with the expectation of having 30 participants completed per study group. Particants will be randomly allocated to use one of the two study products defined in the trial protocol for two months. Up to three study visits will be made by the participant over a 2-month period. All relevant data will be captured and recorded into CTMS (Clinical Trial Management System). The data will be analyzed and reported after the completion of the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
70
The participants in this arm will use the assigned product for 2 months, 5g one time, once a day.
The participants in this arm will use the assigned product for 2 months, 5g one time, once a day.
Ai'er Hospital
Shanghai, Shanghai Municipality, China
SPRIM Central Lab
Shanghai, Shanghai Municipality, China
Skin Elasticity
The changes of skin elasticity from baseline to day 60 by CK Cutometer MPA580
Time frame: baseline day 0, day 60
Skin Moisture
The changes of skin moisture from baseline to day 60 by Corneometer CM 825
Time frame: baseline day 0, day 60
Skin Barrier
The changes of skin barrier in terms of TEWL (Trans Epidermal Water Loss) by Aquaflux F200
Time frame: baseline day 0, day 30, day 60
Lines/Wrinkles
The changes of the lines/wrinkles on the face by Miravex Antera 3D imaging system
Time frame: baseline day 0, day 30, day 60
Facial Glow
The changes of Facial Glow by expert visual assessment
Time frame: baseline day 0, day 30, day 60
Skin Diagnosis
The skin diagnosis (4 modes and 2 side views) with VISIA CR Facial Imaging System
Time frame: baseline day 0, day 30, day 60
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