The goal of this observational study is to learn about changes in oral processing and appetite in older adults aged 65+ years old. The main question it aims to answer is if oral processing affects gastric emptying in older adults (≥65 years old).
* To investigate if food intake and satiety differ between faster and slower eaters, within older adults (≥65 years old). * To assess if chewing rate, salivary flow rate, oral processing and gastric emptying differ between older adults (≥65 years old) with smaller versus bigger appetites.
Study Type
OBSERVATIONAL
Enrollment
88
University of Reading
Reading, United Kingdom
Objective appetite assessment: Ad-libitum meal consumption
Consumption of the ad-libitum meal is measured (g). Participants are instructed to eat until they feel comfortable full
Time frame: During the procedure
Subjective appetite assessment: VAS
Appetite are assessed using a 100 mm Visual Analogue Scales (VAS, scale 0-100)
Time frame: During the procedure
Gastric Emptying
Gastric emptying is measured using of 100 microliters of 13C Octanoic Acid breath test
Time frame: During the procedure
Chewing rate
Chewing rate would be assessed with recording the preload breakfast meal provided and analysing the video recording in software (ELAN 6.4) for number of chews, bites, swallows, time of food in the mouth.
Time frame: During the procedure
Salivary flow rate
Stimulated and unstimulated salivary flow rate would be assessed with passive drooling method.
Time frame: During the procedure
BMI
BMI is assessed by using a body composition monitor (OMRON Viva)
Time frame: During the procedure
Oral Health
Oral Health will be assessed by using an Oral Health Questionnaire
Time frame: During the procedure
Chewing ability
Chewing ability will be assessed by using a colour mixing ability chewing gum test (Heu-Check test, University of Bern)
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Time frame: During the procedure
Glucose
Glucose will be assessed from finger prick blood samples
Time frame: During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours
Insulin
Insulin will be assessed from finger prick blood samples
Time frame: During the procedure. Every 15 minutes for the first hour after the meal and every 30 minutes thereafter till the end of the total 3 hours
Salivary a-amylase
Salivary a-amylase activity will be assessed from the stimulated saliva collected, by using a-amylase kinetic kit
Time frame: During the procedure