Background: Myoclonus dystonia (DYT-SGCE) is characterized by myoclonus and dystonia. Such condition is associated with a high prevalence of psychiatric symptoms which are part of the phenotype. The mechanisms underlying these non-motor symptoms are still poorly understood. Objective: To investigate the neural correlates of cognition and emotion in DYT-SGCE. Design: Participants will have 1 - 2 visits at the clinical center. The total participation time is less than 24 hours. Participants will have a medical interview and a neurological exam. They may give a urine sample before MRI. Participants will have a short neuropsychologic and psychiatric interviews. Participants will have MRI scans. They will do small tasks or be asked to imagine things during the scanning.
Eligibility: DYT-SGCE patients and healthy volunteers (HV) between 15 and 60 years old.
Study Type
OBSERVATIONAL
Enrollment
47
Brain Institute
Paris, Paris, France
BOLD signal derived from the functional magnetic resonance imaging
Explore the differences in DYT-SGCE compared to HV
Time frame: 46 month
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.