Since TAP block needs to affect several nerves in single tissue plane with a single prick, hyaluronidase is expected to aid greatly in the spread of the LA and help the block. However, there have not been adequate studies to establish the efficacy of adding hyaluronidase in lateral TAP after cesarean section. Hence, the present study was carried out to evaluate the efficacy of hyaluronidase in different concentrations added to bupivacaine in US-guided bilateral lateral TAP block.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
114
hyaluronidase will be applied as adjuvant to bupivacaine in transversus abdominis plane block to enhance the postoperative analgesic effect after CS
20ml bupivacaine will be injected without additives in the transversus abdominis plane block on each side for postoperative analgesic after CS
Samar Rafik Amin
Banhā, Qalyubia Governorate, Egypt
the duration of analgesia
the interval between performing the block and the time of the first request for analgesia.
Time frame: 24 hours postoperative
the postoperative pain severity
pain was assessed by the visual analog scale (VAS) pain score (range, 0-10; 0, no pain; 10, worst pain)
Time frame: every 0,2,4,8,12, up to 24 hours postoperative
total morphine consumption
Time frame: at 24 hours postoperatively
patient satisfaction
assessed on a four-point scale (1, excellent; 2, good; 3, fair; 4, poor)
Time frame: at 24 hours postoperatively
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