The goal of this observational study is to test the feasibility of intracoronary adenosine administration during coronary flow reserve(CFR) and index of microcirculatory resistance(IMR) assessment in a population with angina. The main questions it aims to answer are: * Repeatability of CFR and IMR assessment while hyperemia with intracoronary adenosine was administered. * Evaluate the correlation of the intrinsic signal of coronary waveform versus physiologic ischemia, while defined by fractional flow reserve(FFR) and CFR respectively. * The predictive value of FFR, CFR, and IMR on major adverse cardiovascular outcomes in 3 years Participants will undergo FFR, CFR, and IMR assessments in the catheterization laboratory of the National Taiwan University Hospital Hsin-Chu Branch, then clinical events follow up for 3 years.
Study Type
OBSERVATIONAL
Enrollment
30
Participants will undergo repeat intracoronary adenosine administration during CFR and IMR measurement
National Taiwan University Hospital Hsin-Chu branch
Hsinchu, Taiwan
RECRUITINGRepeatability of CFR and IMR value
To compare the difference of individual value, while repeat the measurement within 1 minutes
Time frame: 10 minutes
Major adverse cardiovascular outcomes
Including death, myocardial infarction, stroke and heart failure
Time frame: 3 year
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