Comparison of the analgesic and physical recovery effect of genicular nerve block (GNB) alone and (GNB + infiltration between popliteal artery and posterior capsule of the knee (IPACK) in patients undergoing total knee replacement
Comparison of preemptive analgesia of (GNB) with (GNB+ IPACK) on postoperative pain control and recovery of knee physical activity in patient undergoing total knee replacement.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
63
When patients are in supine position with a pillow under the popliteal fossa, we will target points next to superior medial, superior lateral, and inferior medial genicular arteries to block the superior medial, superior lateral, and inferior medial branches of genicular nerve. For identification, we will use color Doppler near the periosteal areas (the junctions of the epicondyle with the shafts of the femur and tibia, accordingly). using a 12 MHz linear transducer (XarioTM SSA-660A, Toshiba Medical Systems Corporation, Otawara, Japan) positioned parallel to the shaft of the long bones in the legs, the needle will be inserted ( in plane technique in the long-axis view) and a 2.5 mL of bupivacaine (5%) will be injected at each target points.standard analgesia will be given post-operativelly (paracetamol 1 gm/ three times a daily and meloxicam (15 mg)once a day)
IPACK block will be done when the patients in supine position with the knee flexed in 45 degree. using a low frequency transducer at a depth of 3.5-4 cm positioned transversely, 2-3 cm above the patella and over the medial aspect of the knee, we will identify the distal part of the shaft of the femur and the popliteal artery with sliding the transducer proximally and distally (If the two femoral condyles appear first, proximal sliding of the probe, so the humps of the femoral condyles will disappeared and the flat metaphysis will appeared). With advancement of the needle in plane toward the space between the popliteal artery and the femur, 15 ml of bupivacaine 0.5% will be injected. The genicular nerve block will be done as in group G and standard analgesia will be given post-operative as in group G
Heba M Fathi
Zagazig, Egypt
RECRUITING2 hours visual analogue scale
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 2 hour postoperative.
4 hours visual analogue score
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 4 hours postoperative
6 hours visual analogue score
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 6 hours postoperative
8 hours visual analogue score
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 8 hours postopertaive
12 hours visual analogue score
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 12 hours postoperative
18 hours visual analogue score
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 18 hours postoperative
24 hours visual analogue score
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(paracetamol 1 gm 3 times a daily and meloxicam (15 mg) once aday.
pain intensity at rest and with motion using visual analogue scale from " horizontal line of 10-cm long with two ends, one end indicate no pain 0 and the other end indicate worst pain 10".
Time frame: at 24 hours postoperative
• Time of performance of block
defined as time from putting of U.S probe till the end of block procedure.
Time frame: from putting of U.S probe till the end of block procedure
• Total morphine consumption
Total morphine consumption
Time frame: at 24 hours post-operatively
•incidence of Anticipated side effect
nausea, vomiting, itching, hemorrhage, bradycardia and hypotension.
Time frame: at 24,48 hours postoperative
degree of maximum active flexion and extension of the knee
the angle of maximum active flexion and extension of the knee
Time frame: at 24 hours post operative
walk test
walking distance in meters that patients can wake during 2 min
Time frame: at 24 hours post operative
holding quadriceps muscle
number of patients capable to hold quadriceps muscle more than 5 seconds.
Time frame: at 24 hours post operative
time up and go (TUG)
the time required for the patient to stand up from a standard-height armchair, walk 3 meters, turn, walk back to the chair, and sit down
Time frame: at 24 hours post operative