Organosilane for Surface Cleaning in Intensive Care Units

Hospital Israelita Albert Einstein10,301 enrolled

Overview

The purpose of this study is to evaluate if surface disinfection with organosilane associated with traditional cleaning reduces the incidence of healthcare-associated infections (HAIs) in intensive care units when compared with traditional cleaning alone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

10,301

Conditions

Infection, Hospital

Interventions

Surface disinfection with OrganosilaneOTHER

Organosilane will be sprayed on the surfaces, using an atomizer. When the environment has been completely covered (i.e., when all surfaces and equipment have a slightly damp film), we will proceed with the second phase of the disinfection of all heavily touched surfaces. surfaces of the bed, with a microfiber cloth with organosilane.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients aged 18 years and older who will be admitted to the participating ICUs Exclusion Criteria: * Patients under 18 years * ICUs that may use any organosilane formulation for surface disinfection

Locations (14)

Hospital Jean Bittar

Belém, Brazil

Santa Casa de Misericórdia

Belo Horizonte, Brazil

Hospital de Base do Distrito Federal

Brasília, Brazil

Outcomes

Primary Outcomes

Incidence of healthcare associated infections

Time frame: 6 months

Secondary Outcomes

Contamination of environmental surfaces by multi-resistant microorganisms

We will collect environmental samples from 4 surfaces highly touched by the patient, health team and family (bed rails, monitor and infusion pump buttons, meal table or procedure table, and IV drip stand) before and after the intervention. (end of the 6 months). For analysis of the environmental samples, characterization of the density and microbiological profile of biofilms on the different surfaces of the ICU beds will be performed using large-scale DNA sequencing techniques associated with bioinformatics analysis.

Time frame: 6 months

Incidence of ventilator-associated pneumonia

Time frame: 6 months

Incidence of central line-associated blood stream infections

Time frame: 6 months

Incidence of catheter-associated urinary tract infection

Time frame: 6 months

Intensive care unit length of stay costs

Time frame: 6 months

Data from ClinicalTrials.gov

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