This study is intended to be a multicenter, prospective, non-randomized, controlled real-world study. Patients receiving L-carnitine injection were included in the experimental group and the control group according to whether they received L-carnitine injection. Patients receiving L-carnitine injection were included in the experimental group, and those receiving L-carnitine injection were included in the control group.To observe the effects of L-carnitine on cardiac function in hemodialysis patients.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
1,008
The patients in the test group were injected with 1-2g (10-20mg/kg) levocarnitine on each dialysis day
The First Affiliated Hospital of Zhejiang Chinese Medical University
Hangzhou, Zhejiang, China
Change from baseline in Left ventricular ejection fraction
Time frame: baseline and week 12
Change from baseline in Brain natriuretic peptide level
Time frame: baseline ,week 4 and week 12
Change from baseline in left ventricular short axis shortening rate
Time frame: baseline and week 12
Change from baseline in stroke volume
Time frame: baseline and week 12
Change from baseline in the ratio of peak E to peak A of mitral valve blood flow velocity in early and late diastolic periods
Time frame: baseline and week 12
Change from baseline in serum albumin
Time frame: baseline and week 12
Change from baseline in upper arm circumference
Time frame: baseline and week 12
Change from baseline in prealbumin
Time frame: baseline and week 12
Change from baseline in hemoglobin
Time frame: baseline and week 12
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