Antioxidant and Immune Effects of Vitamin K2

Inclusion Criteria: * Self-reported postmenopausal (at least one year after the final menstruation) * BMI ≥25 and ≤32 kg/m2; * Plasma dp-ucMGP concentration in highest 50-66% of the screened population * Non-smoking, defined as not smoking currently and not having smoked (at all) in the year before study start; * Healthy as assessed by the health questionnaire and according to the judgment of the study physician; * Voluntary participation; * Having given written informed consent; * Willing to comply with study procedures; Exclusion Criteria: * Plasma dp-ucMGP concentration \>1000 pmol/L at screening * Treatment with oral antibiotics within 2 months of the start of the study * Any vaccination in the month before study start or any scheduled vaccination during the study period * Use of antioxidant or vitamin K and D supplements; * Use of antioxidant or vitamin K and D supplements in the month before the start of the study; * Use of aspirin or medication with established antioxidant or anti-inflammatory properties; * Use of medication that interferes with vitamin K or blood coagulation; * Use of statins to reduce level of low-density lipoprotein cholesterol in the blood; * Hyperlipidaemia, diabetes, hypertension, intestinal disease, diseases with an inflammation component; * Hormone replacement therapy in women; * Follow a vegetarian or vegan diet; * Participation in any clinical trial including blood sampling and/or administration of substances up to 30 days before day 1 of this study; * Alcohol consumption for men \> 28 units/week and \>4/day; for women: \>21 units/week and \>3/day; * Reported unexpected weight loss or weight gain of \> 3 kg in the month prior to pre-study screening, or intention to lose weight during the study period; * Reported slimming or medically prescribed diet; * Recent blood donation (\<1 month prior to Day 01 of the study); * Not willing to give up blood donation during the study;