Prospective Multicenter Study With the Endomina® Triangulation Platform

Inclusion Criteria: * Patient must be willing to provide written informed consent * Adult patients (between ≥ 18 years (legal age in Europe) and 65 years of age at time of ESG) * Patients who require endoscopic gastroplasty and who are selected by multidisciplinary team/investigators to be treated with the endomina® device and accessories according to the Instructions for Use (IFU) Exclusion Criteria: * Patients with impaired hemostasis or pre-existing conditions that may lead to fragile mucosa (i.e., any contraindication to suturing the stomach) * Any malformation from mouth to esophagus (including pharynx) * Any contraindication to general anesthesia, including patients with cardiorespiratory dysfunction or respiratory failure * Woman who are pregnant, at the time of the procedure or planning (trying) to become pregnant, or nursing within 12 months after the procedure. * Impending surgery 60 days post intervention of the treated section of the GI tract * Participation in another clinical study evaluating another medical device, another procedure or a medication that did not reach its primary endpoint