Determination of the Red Cell Distribution Width, NT-proBNP and cTnT in Acute Myocardial Infarction Patients

Sohag University30 enrolled

Overview

the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute myocardial infarction (AMI) patients.

Patients and methods: * Type of study: Observational prospective study * Place of study: Sohag cardiology and gastroenterology center, department of cardiology and cardiac care unit. * Ethical considerations: This research will be revised by the Scientific Ethical Committee of Sohag University Hospital. Consents will be taken from all patients. * Study Methods: * A prospective study on 30 patients diagnosed as acute myocardial infarction on which measurement of CBC, serum NT-proBNP, and cTnT levels will be performed at the time of admission and by the time of discharge. 1. Full history: 1. Personal history: e.g. age, sex and smoking. 2. Family history of cardiac diseases 3. Medical history of: Hypertension, Ischemic heart disease, prior coronary artery bypass grafting, Prior Percutaneous coronary intervention, Prior Stroke, Prior Atrial fibrillation, therapeutic history 2. Detailed clinical examination 3. Electrocardiogram 4. Laboratory investigation: 1. Routine investigation in the form of CBC including RDW 2. Specific investigation which include NT-proBNP and cTnT

Study Type

OBSERVATIONAL

Enrollment

Conditions

Myocardial Infarction

Interventions

CBCDIAGNOSTIC_TEST

measurement of CBC will be performed at the time of admission and by the time of discharge

(NT-proBNP)DIAGNOSTIC_TEST

measurement of serum NT-proBNP levels will be performed at the time of admission and by the time of discharge

(cTnT)DIAGNOSTIC_TEST

measurement of cTnT levels will be performed at the time of admission and by the time of discharge

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients diagnosed as acute myocardial infarction Exclusion Criteria: Patient with * Decompensated heart failure * Pulmonary hypertention * Acute pulmonary embolism * Septic shock

Outcomes

Primary Outcomes

complete blood count (CBC)

measurement of CBC levels will be performed

Time frame: 7 months

Level of (NT-proBNP)

measurement of serum NT-proBNP level will be performed

Time frame: 7 months

Level of (cTnT)

measurement of cTnT level will be performed

Time frame: 7 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.