Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Iuliu Hatieganu University of Medicine and Pharmacy50 enrolled

Overview

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician. The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Osteoarthritis, Knee Knee Arthritis Gout Arthritis Microcrystal Disease

Interventions

For patients with knee under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physicians. After making the evacuation we will want to use this liquid for Microscopic and Spectrophotometric evaluation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * arthritis of the knee with liquid aspiration recommendation * age \>18 years Exclusion Criteria: --refusal of the patient to participate -age\<18 years

Outcomes

Primary Outcomes

microplastics

evaluation with spectrophotometry and optic microscopy

Time frame: immediately after liquid extraction

nanoplastics

evaluation with spectrophotometry and optic microscopy

Time frame: immediately after liquid extraction